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991.
Relationship between plasma insulin and blood pressure in South African black women in Johannesburg.
OBJECTIVE--To examine the relationship between fasting plasma insulin and blood pressure (BP) in 40 urbanized normotensive South African black women aged 24-60 yr, and to assess the effects of body mass index (BMI) and fasting plasma glucose on BP. RESEARCH DESIGN AND METHODS--The women comprised equal numbers of young nonobese nondiabetic subjects, middle-aged nonobese nondiabetic subjects, middle-aged obese nondiabetic subjects, and middle-aged obese newly diagnosed non-insulin-dependent diabetic subjects. Systolic and diastolic BPs were recorded (in duplicate) after 15 min of recumbency, and fasting plasma glucose and insulin levels were determined thereafter. The data were analyzed by simple and multivariate regression. RESULTS--There was a wide distribution of individual physical and biochemical features. With simple correlations, systolic BP correlated significantly with age, BMI, and fasting glucose but not with insulin. Diastolic BP correlated significantly with all four variables (r = 0.37, P less than 0.05). When adjusted for age, BMI, and glucose, however, the significant correlation between diastolic BP and insulin diminished (r = -0.04). CONCLUSIONS--As in other nonwhite communities, plasma insulin does not appear to play a major role in regulating the BP of South African black women. 相似文献
992.
M Casper S Wing D Strogatz C E Davis H A Tyroler 《American journal of public health》1992,82(12):1600-1606
OBJECTIVES. This study examines the association between increases in antihypertensive pharmacotherapy and declines in stroke mortality among 96 US groups stratified by race, sex, age, metropolitan status, and region from 1962 to 1980. METHODS. Data on the prevalence of controlled hypertension and socioeconomic profiles were obtained from three successive national health surveys. Stroke mortality rates were calculated using data from the National Center for Health Statistics and the Bureau of the Census. The association between controlled hypertension trends and stroke mortality declines was assessed with weighted regression. RESULTS. Prior to 1972, there was no association between trends in controlled hypertension and stroke mortality declines (beta = 0.04, P = .69). After 1972, groups with larger increases in controlled hypertension experienced slower rates of decline in stroke mortality (beta = 0.16, P = .003). Faster rates of decline were modestly but consistently related to improvements in socioeconomic indicators only for the post-1972 period. CONCLUSIONS. These results do not support the hypothesis that increased antihypertensive pharmacotherapy has been the primary determinant of recent declines in stroke mortality. Additional studies should address the association between declining stroke mortality and trends in socioeconomic resources, dietary patterns, and cigarette smoking. 相似文献
993.
994.
甘草叶中两个新异戊烯基黄酮类化合物 总被引:3,自引:0,他引:3
自乌拉尔甘草(Glycyrrhiza uralensis Fisch.)的干燥叶中分离到三个黄酮类化合物。经化学方法和光谱(UV,MS,1HNMR)数据分析,分别确定为5,7,3′,4′-四羟基-3-甲氧基-5′-异戊烯基黄酮(Ⅰ),5,6,3′,4′-四羟基-3-甲氧基-6′-异戊烯基黄酮(Ⅱ)和槲皮素(Ⅲ)。Ⅰ和Ⅱ是新化合物,分别命名为乌拉尔醇-3-甲醚(uralenol-3-methylether)和乌拉尔素(uralene)。Ⅲ在本种植物中为首次报道。 相似文献
995.
L H Epstein J McCurley R R Wing A Valoski 《Journal of consulting and clinical psychology》1990,58(5):661-664
This article presents the 5-year outcome of family-based behavioral treatment of obesity for 6- to 12-year-old children in 162 families across 4 treatment outcome studies. Results suggest that treatments that use (a) conjoint targeting and reinforcement of child and parent behavior or (b) reciprocal targeting and reinforcement of children and parents are associated with the best child outcomes. Predictors of child success include self-monitoring, changing eating behavior, praise, and change in parent percent overweight. Parental outcome is predicted by self-monitoring weight, baseline parent percent overweight, and participation in fewer subsequent weight control programs. 相似文献
996.
Wing Hong Loke 《Human psychopharmacology》1992,7(6):379-388
The present study examined caffeine's effect on mental performance in contrast to a recent study (Loke and Goh, 1992) which examined the effects of caffeine user-effect on mental performance. Taken together, the studies would provide a detailed understanding of the effects of caffeine and automaticity on the visual search/detection domain of information processing. Analyses of the baseline measures of the visual search/detection task showed significant differences between low and high levels of automaticity and levels of task difficulty. Performance on the low difficulty level was higher than the high difficulty level, and performance on automatic task was higher than on non-automatic task. Caffeine, however, did not interact with automaticity and task difficulty. Therefore, given that the present study used unpractised (novice) subjects with similar levels of caffeine consumptions and personality characteristics, the visual search/detection domain of information processing is shown to be insensitive to the effects of caffeine. This supports the general view that caffeine does not affect cognition, learning, and memory performance. Also, the non-significant three-way interaction of drug, automaticity, and task difficulty would therefore suggest that caffeine does not affect resource capacity. Of note is that knowledge of drug administration assessments (drug guessing) was sensitive to the effects of caffeine in the automatic condition and not in the non-automatic condition, suggesting that the effects of caffeine are task-dependent. In contrast, the expected sensitivity of mood assessments to caffeine's effects was not shown. Since caffeine is shown to be a ‘weak’ stimulant, given its commonly known non-significant effects on mental performance, caffeine-administered subjects may lack sufficient external cues to allow them to perceive and report correctly that they were given caffeine. 相似文献
997.
Influences of natural menopause on psychological characteristics and symptoms of middle-aged healthy women 总被引:3,自引:0,他引:3
K A Matthews R R Wing L H Kuller E N Meilahn S F Kelsey E J Costello A W Caggiula 《Journal of consulting and clinical psychology》1990,58(3):345-351
We investigated the psychological and symptom consequences of the natural menopause in a longitudinal study of 541 initially premenopausal healthy women. All women were given an extensive evaluation at baseline. After 3 years of follow-up, 69 women ceased cycling for 12 months; another 32 women had ceased cycling and had taken hormone replacement therapy for a total of 12 months. These women were reevaluated in a clinic examination identical with the baseline examination, as were 101 age-matched premenopausal control women. Comparison among groups at the baseline and follow-up examination showed that natural menopause led to few changes in psychological characteristics, with only a decline in introspectiveness and an increase in reports of hot flashes being apparent. We conclude that natural menopause did not have negative mental health consequences for the majority of middle-aged healthy women. 相似文献
998.
A 37 year old Chinese man suffered from coexisting narcolepsy and morbid jealousy which were precipitated by head injury 5 years previously. Fluoxetine 20 mg/day reduced his narcoleptic symptoms and morbid jealousy but not his sleepiness. On defaulting treatment, the patient''s symptoms and marital problem recurred. A common central serotonin disturbance might be involved in mediating the sleep disorder and associated psychopathology. 相似文献
999.
Neutrophil elastase digests plasminogen to yield a fragment, mini-plasminogen, which is activatable to a mini-plasmin capable of escaping the action of the primary plasmin inhibitor. Such a molecule may play a role in joint destruction, either directly or by activation of procollagenase to collagenase. Synovial fluid samples from 34 acute joint effusions were examined by lysine-Sepharose chromatography and fibrinolytic assay of the fall-through (non-lysine-binding) fractions in presence of urokinase. Fragments similar to mini-plasminogen were found in 20 of 23 inflammatory effusions (cell count greater than 0.5 X 10(3)/microliter) and in none of 11 non-inflammatory (traumatic and osteoarthritic) effusions (cell count less than 0.5 X 10(3)/microliter) (p less than 0.001). Analysis of four inflammatory fluids by gel filtration on Bio-Gel P 100 and enzyme-linked immunoassay for plasminogen antigen revealed plasminogen fragments with molecular weight similar to mini-plasminogen (34,000 daltons) in three, and larger plasminogen fragments (or complexes of mini-plasminogen with other synovial fluid macromolecules) in all four. Fibrinolytic activity was demonstrable in fractions containing plasminogen fragments after treatment with tissue type plasminogen activator. In contrast with non-inflammatory effusions, inflammatory joint fluids contain plasminogen fragments with the properties of mini-plasminogen, suggesting their possible role in inflammatory joint destruction. 相似文献
1000.
Rajesh Garg Boris KK Fung Shew Ping Chow Wing yuk Ip 《Journal of orthopaedic surgery and research》2007,2(1):4-3
We present a case report of a free thenar flap surgery done for a volar right hand middle finger, distal and middle phalanx
degloving injury. A free thenar flap is a fasciocutaneous sensate flap supplied by a constant branch of the superficial radial
artery and its variable nerve supply. It has a distinct advantage of low donor site morbidity, better cosmesis and texture
of the flap. No immobilization is required postop. The donor site can be closed primiarily. 相似文献